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Answer:

We have spotted DEPLETE (7 Letters) a total of 4 times in our database. Below you may see the clues associated with DEPLETE and also when and where was it last seen:

Definition

To empty or unload, as the vessels of human system, by bloodletting or by medicine.
To reduce by destroying or consuming the vital powers of; to exhaust, as a country of its strength or resources, a treasury of money, etc.

Referring crossword puzzle clues

Usage among publishers: